The World Health Organization (WHO) has declared monkeypox a “public health emergency of international concern” (PHEIC) – designed to prompt a coordinated international response. The last time the WHO made such a designation was in January 2020 in response to the Covid-19 outbreak.
To date, more than 16,000 cases have been reported in more than 75 countries and the number of confirmed infections has risen 77% from late June through early July, according to WHO and UN data.
The World Economic Forum’s Head of Health and Healthcare, Dr Shyam Bishen, says, “With this declaration, countries will need to invest significant resources in controlling this outbreak.”
Upscaling of vaccines and treatment needed
He adds, “Fortunately, vaccines and drugs developed for smallpox may work well against monkeypox. But there is a very limited supply. While we encourage nations to share vaccines, treatments and other key resources for containing the outbreak, we believe a multistakeholder partnership is necessary among private sector, governments, and international organizations to quickly scale-up vaccine and treatment production for this disease.”
Europe is currently the epicenter of the outbreak, reporting more than 80% of cases worldwide this year. There have been no deaths reported from the virus outside of Africa, where there have been five to date.
While considered high in Europe, the global risk remains moderate and is unlikely to disrupt travel or trade.
The virus was discovered in 1970 and previous cases had been mainly in Africa. Cases outside of Africa have historically been rare, traced back to infected travellers or imported animals.
Here’s what you need to know about monkeypox and how public health authorities worldwide are responding.
What is monkeypox?
The monkeypox virus is a type of orthopoxvirus, in the same family of virus that causes smallpox. The symptoms of monkeypox are similar – though less severe and less contagious – than smallpox.
How does monkeypox spread?
Monkeypox is classified as a zoonosis, which means a disease that is transmitted between humans and animals. Cases often appear in tropical climates and rainforests where there are animals carrying the virus, including types of squirrels, dormice and certain types of monkeys and rats. The disease is transmitted through bites, scratches or bush meat preparation.
Human-to-human transmission is limited and the virus is transmitted through direct contact with bodily fluids or skin lesions as well as indirect contact with lesion materials through items such as contaminated bedding or clothing.
How is it treated?
There is currently no medication for the monkeypox virus itself. However, the antiviral drugs cidofovir, brincidofovir and tecovirimat may be used.
The WHO is currently convening experts to discuss recommendations on vaccination.
How are public health authorities responding?
According to the WHO, health authorities are responding through the following measures:
- Ongoing public health investigations in non-endemic countries that have identified cases, including contact tracing, lab investigation, clinical management and isolation with supportive care.
- Genomic sequencing, where available, has determined the monkeypox virus clade(s) infecting individuals. Scientists are working to determine if the recent infections in Europe are related to strains in Africa.
- Vaccination for monkeypox, where available, is being deployed to manage close contacts, such as health workers.
- Robust surveillance, contact tracing and infection prevention and control: Strong surveillance and diagnostic systems, partnered with swift information-sharing, has ensured that health authorities can rapidly report and communicate on the outbreak.
- The WHO has also released emergency funds to countries with limited testing capabilities and supplies to establish monkeypox virus identification and sequencing.
This article was written by Dr Shyam Bishen and Kelly McCain and was first published on The World Economic Forum.